Investigation of tramadol pharmacokinetics and clinical responses in Japanese patients with head and neck cancer receiving oral tramadol
Not Applicable
- Conditions
- cancer pain
- Registration Number
- JPRN-UMIN000039308
- Lead Sponsor
- Department of Hospital pharmacy Hamamatsu University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients discontinuing oral tramadol 2. Patients having severe kidney dysfunction or liver dysfunction 3. Patients who have a difficulty in determination of genotype using peripheral blood sample 4. Patients who are judged by physicians as inappropriate for study enrollment
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma concentrations of tramadol, O-desmethyltramadol, N-desmethyltramadol and N,O-didesmethyltramadol 96 hours and later starting oral tramadol.
- Secondary Outcome Measures
Name Time Method