Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery: a Prospective Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiorenal Syndrome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- change in renal glomerular filtration before and 6 hours after use of diurectic
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow. The investigator's standard care includes use of diuretic to avoid interstitial fluid accumulation. The aim of the study is to assess cardiac and renal function before and after depletion by using diuretics
Detailed Description
The study will compare cardiac and renal data before and 6 hours after use of diuretic * Echocardiographic measure of right function (S wave, TAPSE, ventricle surfaces, inferior vena cava diameter) and left function (LVEF, cardiac output * Renal function: cumulative diuresis, creatinine level variation and incidence of acute kidney injury using KDIGO classification (creatinine level\>26.5 or diuresis\<0.05 ml kg-1 h-1)
Investigators
Eligibility Criteria
Inclusion Criteria
- •patient undergoing elective cardiac surgery under cardiopulmonary bypass
Exclusion Criteria
- •heart transplantation
- •use of vasopressor
- •chronic renal disease (DGF under 30 ml min-1)
- •endocarditis
- •patient under ECLS or CPIA
- •patient under 18-year-old
Outcomes
Primary Outcomes
change in renal glomerular filtration before and 6 hours after use of diurectic
Time Frame: at baseline (o hours) and 6 hours after use of diuretic
change in renal glomerular filtration before and 6 hours after use of diurectic