Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery
- Conditions
- Cardiorenal Syndrome
- Registration Number
- NCT03684876
- Lead Sponsor
- Centre Hospitalier Universitaire, Amiens
- Brief Summary
Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow. The investigator's standard care includes use of diuretic to avoid interstitial fluid accumulation. The aim of the study is to assess cardiac and renal function before and after depletion by using diuretics
- Detailed Description
The study will compare cardiac and renal data before and 6 hours after use of diuretic
* Echocardiographic measure of right function (S wave, TAPSE, ventricle surfaces, inferior vena cava diameter) and left function (LVEF, cardiac output
* Renal function: cumulative diuresis, creatinine level variation and incidence of acute kidney injury using KDIGO classification (creatinine level\>26.5 or diuresis\<0.05 ml kg-1 h-1)
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 40
patient undergoing elective cardiac surgery under cardiopulmonary bypass
- heart transplantation
- use of vasopressor
- chronic renal disease (DGF under 30 ml min-1)
- endocarditis
- patient under ECLS or CPIA
- patient under 18-year-old
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method change in renal glomerular filtration before and 6 hours after use of diurectic at baseline (o hours) and 6 hours after use of diuretic change in renal glomerular filtration before and 6 hours after use of diurectic
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHU Amiens Picardie
🇫🇷Amiens, France