IMPACT OF VAMANA KARMA(THERAPEUTICALLY INDUCED EMESIS) AND TRIPHALA AND GUDUCHI CHURNA WITH MADHU ON THE MODULATION OF GUT MICROBIOTA.

Phase 4

• Conditions: Health Condition 1: E119- Type 2 diabetes mellitus without complicationsHealth Condition 2: E119- Type 2 diabetes mellitus without complications

• Registration Number: CTRI/2020/12/030107
• Lead Sponsor: All India Institute of Ayurveda

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

For Prameha(Type 2 Diabetes Mellitus) Individuals-

1. BMI� 20

2. Kaphaj/Kapha-pittaj Vikriti predominant individuals

3. Diagnosed cases of Prameha/Madhumeha/T2DM with either of the following-

a) Fasting plasma glucose values of � 7.0 mmol/L (126 mg/dl)

b) 2-h post-load plasma glucose � 11.1 mmol/L (200 mg/dl)

c) HbA1c � 6.5% (48 mmol/mol)

d) Random blood glucose � 11.1 mmol/L (200 mg/dl)

4. Chronicity: Up to 10 years

For Healthy Individuals

1. BMI� 20

2. Kaphaj/Kapha-pittaj Prakriti predominant Individuals as per Proforma for Prakriti Assessment by CSIR Ayurgenomics Unit- TRISUTRA CSIR-IGIB, NEW DELHI

3. Healthy individuals as per Proforma for Health Assessment by self-reporting of CSIR Ayurgenomics Unit- TRISUTRA CSIR-IGIB, NEW DELHI

Exclusion Criteria

Patients unfit for Snehana(Internal Oleation), Svedana(Sudation), Vamana(therapeutically induced emesis for internal bio-cleansing).

For Prameha(Type 2 Diabetes Mellitus)-

1. Patients with T2 DM exceeding the following plasma glucose limits-

a) Fasting plasma glucose values of � 300mg/dL

b) 2-h post-load plasma glucose�400mg/dL

c) Random blood glucose� 400mg/dL

2. Chronicity: More than 10 years.

3. Known cases of Severe systemic diseases like- Cardiac disease, pulmonary tuberculosis, severe lung disease, uncontrolled diabetes and pregnant women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified