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Improving the early diagnosis of Alzheimer*s disease and other dementias

Conditions
dementia
mental disorder
10042258
10012272
Registration Number
NL-OMON29838
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
320
Inclusion Criteria

1) complaints of decline in cognitive or behavioural functioning (expressed by patient or close relative);
2) age between 50 and 85 years.

Exclusion Criteria

1) dementia as established by a dementia specialist according to DSM-IV criteria;
2) other brain disease or systemic disease sufficient to cause the complaints and symptoms;
3) current substance abuse or addiction;
4) serious somatic disease or handicap that prevents neuropsychological evaluation;
5) pre-existent mental retardation;
6) contra-indication for MRI scanning;
7) insufficient command of the Dutch language.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Clinical status at follow-up after 2, 4 or 6 years (demented / stable /<br /><br>improved).</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Abnormal results of MRI.</p><br>
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