The effect of eradication of Helicobacter pylori infection in the treatment of rosacea
Phase 3
Recruiting
- Conditions
- Rosacea.Rosacea
- Registration Number
- IRCT20201116049400N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Age 17-56
Subjects with rosacea
Exclusion Criteria
Gastrointestinal symptoms (bloating, nausea, high intestinal upset, premature satiety, heartburn, ...)
Age less than 17 and more than 65 years
Antibiotics ( Bismuth subsalicylate) for the treatment of Helicobacter pylori eradication
Use of proton pump inhibitors (Nexium and Prilosec) during the month before the start of the study
Pregnancy or Breastfeeding
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determination of Immunoglobulin G (IgG) and Immunoglobulin M (IgM) levels of Helicobacter pylori and qualitative determination of Helicobacter pylori antigens. Timepoint: Measurement of IgG and IgM levels of Helicobacter pylori , evaluation of the presence of Helicobacter pylori antigen in the feces of patients and lesion size (before the intervention) and 2 months after the start of topical antibiotics and gels. Method of measurement: ELISA (Enzyme-Linked Immunosorbent Assay), EIA (Enzyme Immunoassay).
- Secondary Outcome Measures
Name Time Method