Chronic Pain Dynamic Psychophysical Tests and Genetic Screening

Completed

• Conditions: Pain

• Registration Number: NCT02373696
• Lead Sponsor: KK Women's and Children's Hospital

Brief Summary

Incidence and risk factors for persistent post surgical pain after Caesarean section are investigated. Demographic, psychophysical testing and genetic screening factors are performed in the perioperative period. Phone survey is performed to investigate the incidence of persistent post surgical pain after Caesarean section.

Detailed Description

Persistent post surgical pain after Caesarean section may lead to functional limitation and pain during activities of daily living. Demographic factors, psychophysical factors (mechanical temporal summation, diffuse noxious inhibitory control, state trait anxiety inventory) and genetic screening are used to predict the association with persistent post surgical pain. Phone survey follow up is performed to investigate the incidence of persistent post surgical pain and functional limitations due to pain experienced.

Study Timeline

• Study Start: 2010-04
• Primary Completion: 2015-01
• Study Completion: 2015-01
• Study First Submitted: 2015-02-22
• Study First Submitted QC: 2015-02-22
• Study First Posted: 2015-02-27
• Status Verified: 2015-09
• Last Update Submitted: 2015-09-03
• Last Update Posted: 2015-09-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 178

Inclusion Criteria

• Women undergoing spinal anaesthesia for Caesarean section

Exclusion Criteria

• Failed spinal anaesthesia, Unable to perform psychophysical testing.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Persistent Postsurgical Pain	12 weeks	Pain experienced in the lower abdominal region and surgical area after Caesarean section

Trial Locations

Locations (1)

KK Women's and Children's Hospital; 🇸🇬 Singapore, Singapore