A comparative study on differences in control methods for moderate or severe cancer pai

Not Applicable

• Conditions: Neoplasms

• Registration Number: KCT0008879
• Lead Sponsor: CHUNGNAM NATIONAL UNIVERSITY SEJONG HOSPITA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 176

Inclusion Criteria

? A person diagnosed with cancer
? Uncontrolled cancer pain (in this study, those whose average pain intensity was 7/10 or higher on a numerical scale over the past 24 hours)
? Hematology oncology inpatient and outpatient
? Those who use oral morphine, oral oxycodone, oral oxycodone/naloxone (targin), or oral hydromorphone as background drugs
? Those who use strong opioids with a morphine equivalent daily dose of 30-300mg
? Those whose Karnofsky performance status was >= 50% before registration
? Age 19 or older at the time of registration
? Those with normal kidney and liver function

Exclusion Criteria

? Those with delirium (i.e. Memorial delirium rating scale >13)
? Those with a history of substance use disorder within the past 12 months
? Those who are allergic to morphine
? Those who refuse to consent in advance
? Those who have pain only in certain positions
? Those who need opioid circulation due to toxicity
? Those who cannot take oral medication
? CAGE score >= 3
? Minors/pregnant women, fetuses, newborns/adults with impaired consent/students, employees/prisoners, etc. in vulnerable environments

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The difference in pain control between switching background opioid group (SG) and keeping background opioid group (KG) for two hours - pain control is defined as Numeric rating scale (NRS) = 3 or more points of pain reduction.

Secondary Outcome Measures

Name	Time	Method
Side effects associated with the use of SC fentanyl (e.g., drowsiness, nausea, congestion) are evaluated using a numerical rating scale of 0-10. Satisfaction asks questions about the patient's pain. (Pain control satisfaction %)