Determinants of Cognitive Impairment Among Geriatrics

• Conditions: Dyslipidemias; Osteoarthritis; Dementia; Hearing Impairment; Diabetes; Depression; Obesity; Hypertension; Mobility Limitation; Cognitive Impairment

• Registration Number: NCT03669536
• Lead Sponsor: Tarumanagara University

Brief Summary

This study aims to explore the determinants of cognitive impairment among Indonesian geriatrics in an Old Age Home.

Detailed Description

Elderly patients (≥ 60 years of age) are enrolled in this study. The inclusion criteria are patients which have consented to take part in the study.

Data such as age, ethnic, education, BMI, waist and hip circumference, blood pressure, hearing impairment, vision impairment, depression, sleep disorder, mobility, hemoglobin levels, glycemic and lipid profile, as well as comorbidities and drugs used were collected from the patients' medical records, laboratory tests and through examination by trained examiners.

Cognition was determined through a combination of several psychiatric examinations using validated instruments namely - MiniCog, Clock Drawing Test, Three Word Recall, Alzheimer's Disease-8 Indonesia (AD-8 INA) Questionnaire and Short Portable Mental Status Questionnaire (SPMSQ).

Study Timeline

• Study Start: 2017-08-01
• Status Verified: 2018-09
• Study First Submitted: 2018-09-10
• Study First Submitted QC: 2018-09-11
• Last Update Submitted: 2018-09-11
• Study First Posted: 2018-09-13
• Last Update Posted: 2018-09-13
• Primary Completion: 2018-12
• Study Completion: 2018-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Must be classified as geriatric according to Indonesian Laws (≥ 60 years of age).
• Consented to participate in this study.

Exclusion Criteria

• Uncooperative.
• Incomplete records.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MiniCog	Through study completion, an average of 6 months	Based on psychiatric examination using the Indonesian MiniCog Questionnaire to determine patient's cognitive status. A MiniCog result below 5 implies mild cognitive impairment, while a result below 3 implies dementia.
Three Word Recall	Through study completion, an average of 6 months	Based on psychiatric examination using the Indonesian Three Word Recall Test to determine patient's cognitive status with resulting score from 0-3. Zero means no words can be recalled by the patient.
Short Portable Mental Status Questionnaire (SPMSQ)	Through study completion, an average of 6 months	Based on psychiatric examination using the Indonesian SPMSQ to determine patient's cognitive status. An SPMSQ test in which the patient demonstrated more than 3 mistakes implies mild cognitive impairment, whereas a mistake of greater than 8 implies dementia.
Alzheimer Disease-8 Indonesia Questionnaire (AD-8 INA)	Through study completion, an average of 6 months	Based on interviews with caretakers using the AD-8 INA Questionnaire to determine patient's cognitive status. An AD-8 INA score of 2 or more implies mild cognitive impairment.
Clock Drawing Test (CDT)	Through study completion, an average of 6 months	Based on psychiatric examination using the Indonesian Clock Drawing Test to determine patient's cognitive status. A Clock Drawing Test score below 4 implies mild cognitive impairment.

Trial Locations

Locations (1)

Hana Old Age Home; 🇮🇩 Tangerang, Banten, Indonesia