NCT04187638Unknown不适用
Effect of Olive Oil Consumption on Cardiovascular Biomarkers in Asians and Caucasians: A Randomized, Crossover, Controlled Interventional Trial
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- changes in ambulatory blood pressure
研究概览
简要总结
The main aim of this study is to examine the effect of olive oil consumption on several cardiovascular risk markers between Caucasians and Asian ethnicity. The primary assessments: endothelial function's biomarkers: cell and vascular adhesion molecules (ICAMs and VCAMs) and nitric oxide (NO). The secondary assessments: Lipid profile.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Orient Asians (including Chinese, Japanese, Korean, and Malaysia Chinese) and Caucasians
- •Age 18-70 years
- •Self-reported in good general health
排除标准
- •Age older than 70 years or younger than 18 years
- •Diagnosed and/or are taking medications for hypertension (>140/90mmHg)
- •High blood cholesterol
- •Heart problems (e.g. arrhythmia, high-grade stenosis of the carotid artery or carotid sinus syndrome)
- •Allergy to olive oil or olive oil products
- •Lactose intolerance
- •Taking omega-3 supplements in fish oil and vitamins supplements in the last six months.
结局指标
主要结局
changes in ambulatory blood pressure
时间窗: Baseline and 2 weeks
次要结局
- Changes in vascular cell adhesion molecule 1(Baseline and 2 weeks)
- Changes in plasma total cholesterol(Baseline and 2 weeks)
- Changes in Intercellular Adhesion Molecule 1(Baseline and 2 weeks)
- Changes in C-reactive protein(Baseline and 2 weeks)
研究者
Jose Lara Gallegos
Senior Lecturer
Northumbria University
研究点 (2)
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