The Impact of Exercise Training on Functional Capacity in Heart Failure

Not Applicable

• Conditions: Heart Failure With Preserved Ejection Fraction
• Interventions: Behavioral: Exercise training

• Registration Number: NCT01288365
• Lead Sponsor: Meir Medical Center

Brief Summary

The purpose of this study is to determine whether exercise training will improve functional capacity in patients with heart failure and preserved ejection fraction.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-01-26
• Study First Submitted QC: 2011-02-01
• Study First Posted: 2011-02-02
• Study Start: 2011-03
• Status Verified: 2012-03
• Last Update Submitted: 2012-03-16
• Last Update Posted: 2012-03-19
• Primary Completion: 2012-12
• Study Completion: 2013-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Clinical heart failure
• Preserved ejection fraction (>50%)
• Stable clinically
• New York Heart Association Class II-III

Exclusion Criteria

• Unable to exercise
• Other debilitating or unstable disease limiting length of life
• Implanted pacemaker

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Exercise training	Exercise training	Protocol of 3 month exercise training program.

Primary Outcome Measures

Name	Time	Method
Change from baseline of peak oxygen uptake on graded exercise.	After 3 month exercise training	Changes in physical fitness after 3 month exercise training. This will be measured by a cardiopulmonary exercise test with recording of maximal oxygen uptake during incremental exercise.

Secondary Outcome Measures

Name	Time	Method
Change from baseline of six minute walk	After 3 month exercise training	Change in the distance covered during a 6 minute walk after 3 month exercise training.
Change from baseline of NYHA class	After 3 month exercise training	Change in subjective assessment of function capacity based on the New York Heart Association Class classification after 3 month exercise training.

Trial Locations

Locations (1)

Hadassah University Hospital; 🇮🇱 Jerusalem, Israel