Survey and Blood Sample Collection for Patients With Lung Cancer Who Never Smoked Cigarettes
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- Feasibility of an internet-based protocol to collect clinical information and biological specimens
研究概览
简要总结
RATIONALE: Gathering health information about patients with non-small cell lung cancer who never smoked cigarettes may help doctors learn more about the disease. Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about cancer and identify biomarkers related to cancer.
PURPOSE: This research study is studying internet-based clinical information and blood sample collection from patients with non-small cell lung cancer who never smoked cigarettes.
详细描述
OBJECTIVES:
- To assess the feasibility of an internet-based protocol to collect clinical information and biological specimens from 2,000 never smokers with non-small cell lung cancer.
- To perform genome-wide association studies to identify alleles that predispose to lung cancer in patients that never smoked cigarettes.
OUTLINE:
Patients complete an internet-based questionnaire using the REDCap (Research Electronic Data Capture) survey to determine eligibility. The survey consists of a detailed smoking questionnaire and questions to collect information regarding diagnosis, sex, age, ethnicity, treatment history, and any history of previous malignancies. Blood samples are then collected from eligible patients for DNA and other laboratory analyses. Patients' pathology reports are also reviewed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years or older
- •histologically and/or cytologically proven diagnosis of non-small cell lung cancer
- •never smoker, defined as having smoked less than 100 cigarettes over one's life-time
- •completed survey and inclusion form
- •signed informed consent
排除标准
- •previous history of cancer (other than lung cancer, except for superficial skin cancers)
- •living outside the United States
- •patients who cannot read English (as materials will only be written in English)
- •unable to understand the protocol or to give informed consent
结局指标
主要结局
Feasibility of an internet-based protocol to collect clinical information and biological specimens
时间窗: Six months following collection of final patient data and biospecimen
Identification of alleles that predispose to lung cancer via genome-wide association studies
时间窗: one year following collection of final patient data and biospecimen
次要结局
未报告次要终点