Assessment of Cognitive Functioning as it Relates to Risk for Suicide in Veterans With HIV/AIDS
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Outcome Questionnaire (OQ-45)
Study Overview
Brief Summary
The purpose of this project is to gather pilot data related to exploring relationships between cognitive impairment and/or psychiatric distress and suicidal thoughts and/or behaviors in Veterans with Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS). To achieve this goal, a neuropsychological battery will be administered to Veterans with HIV/AIDS.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Other
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Veterans between ages 18 to 65
- •Have a diagnosis of HIV/AIDS confirmed via medical record
- •Currently receiving or eligible to receive physical and/or mental health care through the VA Eastern Colorado Health Care System
Exclusion Criteria
- •Acute intoxication via alcohol or other illicit drugs at time of assessment as determined by observation and/or interview.
- •Psychosis at time of interview as determined by observation and/or interview.
- •Poor Test of Memory Malingering (TOMM) performance (scores below 25 on Trial 1 or scores lower than 45 on Trial 2)
- •Current status as a prisoner
Outcomes
Primary Outcomes
Outcome Questionnaire (OQ-45)
Time Frame: 1 Time Administration
The OQ-45 is a 45-item questionnaire that was designed to measure key areas of mental health functioning (symptom distress, interpersonal functioning, and social role).
Delis-Kaplan Executive Function System (D-KEFS)
Time Frame: 1 Time Administration
Measure of executive functioning.
Trail Making Test (TMT): Parts A & B
Time Frame: 1 Time Administration
The TMT is a timed, pencil-paper, measure of attention, speed, and cognitive flexibility and requires participants to draw a line to accurately sequence 25 circles containing numbers (Part A) and alternating letters and numbers (Part B).
California Verbal Learning Test, Second Edition (CVLT-II)
Time Frame: 1 Time Adminstration
The CVLT-II examines several aspects of verbal learning, organization, and memory.
Brief VisuoSpatial Memory Test-Revised (BVMT-R)
Time Frame: 1 Time Administration
The BVMT-R measures immediate and delayed visual memory.
Wisconsin Card Sorting Test (WCST)
Time Frame: 1 Time Administration
Measure of executive functioning.
Beck Scale for Suicide Ideation (BSS)
Time Frame: 1 Time Administration
The BSS is a 19-item scale that assesses severity of suicide ideation.
Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV)
Time Frame: 1 Time Administration
The WAIS-IV is a widely used and well established instrument used to assesses an individual's intellectual functioning within various cognitive domains and organizes performance into several indices including Verbal Comprehension Index, Perceptual Reasoning Index, Working Memory Index, and Processing Speed Index. A composite, Full Scale IQ, is also generated to represent an estimation of overall intellectual functioning.
Secondary Outcomes
- Health Status Questionnaire (HSQ)(1 Time Administration)
- Participant Demographics Form(1 Time Administration)
- Military Suicide Research Consortium (MSRC) Common Data Elements(1 Time Administration)
- Test of Memory Malingering (TOMM)(1 Time Administration)
- Ohio State University TBI-ID (OSU TBI-ID) Short Form(1 Time Administration)
- The Beck Anxiety Inventory (BAI)(1 Time Administration)
- University of Washington Risk Assessment Protocol-Revised (UWRAP)(1 Time Administration)
- The Structured Clinical Interview for DSM-IV-Research Version (SCID-I)(1 Time Administration)
- Lifetime Suicide Attempt Self Injury Interview (L-SASI)(1 Time Administration)
- Beck Hopelessness Scale (BHS)(1 Time Administration)
- The Beck Depression Inventory (BDI-II)(1 Time Administration)