Evaluation of clinical efficacy of intramuscular of autologous total IgG in patient with severe atopic dermatitis of refractory to dupilumab therapy
Not Applicable
Active, not recruiting
- Conditions
- Diseases of the skin and subcutaneous tissue
- Registration Number
- KCT0006092
- Lead Sponsor
- Ajou University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
1. Adult patients with recalcitrant atopic dermatitis (age = 19 years) whose clinical conditions has not been effectively controlled by dupilumab treatment.
2. Compatible with the criteria for autologous blood donation (body weight =32 kg)
Exclusion Criteria
Exclusion criteria
1) Patients under the age of 19 year.
2) Patients who are unable to agree on their own (emergency patients, patients with mental disability, patients with limited capacity to consent due to stroke or delirium caused by diabetes).
3) Patients with severe disease whose expected survival duration is less than 3 months.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of clinical efficacy
- Secondary Outcome Measures
Name Time Method Evaluation of anti-allergy effect;Evaluation of immunomodulatory effect;Evaluation of quality of life effect