KCT0007504
Recruiting
未知
The Postoperative Radiotherapy after Breast Conserving Surgery or Mastectomy in N1 Breast Cancer Patients: A Prospective, Multicenter, Phase III Clinical Trial (PORT-N1)
ConditionsNeoplasms
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Neoplasms
- Sponsor
- Seoul National University Hospital
- Enrollment
- 1106
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients aged 19 years or older.
- •\-A female patient who underwent breast\-conserving surgery or mastectomy for invasive breast cancer.
- •\-Patient with stage pN1 after surgery on histopathologic examination.
- •\*\* However, if mastectomy was performed, 5 or more nodes should be resected in the case of 1 positive node, and axillary lymph node dissection (ALND) should be performed in case of 2 or 3 positive nodes.
- •\-Patients undergoing or planning to undergo hormone therapy in the case of hormone receptor positive.
- •\-Patients who have received or are expected to undergo targeted therapy in the case of HER\-2 positive.
- •\-Patients with Eastern Cooperative Oncology Group (ECOG) Scale 0\-2\.
- •\-Patients who agreed to participate in the study.
Exclusion Criteria
- •\-Patients who have received prior \[neoadjuvant] chemotherapy.
- •\-Patients receiving radiation therapy for salvage or palliative purposes.
- •\-Patients with stage T4\.
- •\-Patients with ipsilateral supraclavicular and internal mammary lymph node metastases or distant metastases.
- •\-Male breast cancer patient.
- •\-Patients who have previously received radiation therapy to the ipsilateral breast or supraclavicular region.
- •\-Patients having a history of cancer other than thyroid cancer, cervical carcinoma in situ, or skin cancer.
- •\-Patients diagnosed with ductal breast carcinoma in situ, lobular carcinoma in situ, phyllodes, metaplastic cancer, or benign tumors based on histological diagnosis.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Phase 3
The Postoperative Radiotherapy in N1 Breast Cancer PatientsRadiotherapyBreast CancerNCT05440149Seoul National University Hospital1,106
Recruiting
Not Applicable
ltra-hypofractionated Breast Radiotherapy After Breast-Conserving Surgery for Early-Stage Breast CancerBreast CancerJPRN-UMIN000047080Kobe City Medical Center General Hospital98
Not yet recruiting
Not Applicable
ecessity of post-mastectomy radiotherapy in breast cancer patients with an excellent response after neoadjuvant chemotherapy: A phase 3, multicenter, randomized controlled study (NEMESIS)KCT0008817Yonsei University Health System, Gangnam Severance Hospital1,314
Recruiting
Not Applicable
Breast reconstruction and neoadjuvant radiotherapy, a changing algorithm.breast cancermalignant neoplasm of the breast1000629110006295NL-OMON51819niversitair Medisch Centrum Utrecht20
Not yet recruiting
Phase 3
Necessity of Post-mastectomy Radiotherapy After Neoadjuvant Chemotherapy and MastectomyBreast CancerNCT05993559Gangnam Severance Hospital1,314