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临床试验/EUCTR2008-001092-29-SE
EUCTR2008-001092-29-SE进行中(未招募)不适用

Effect of glimepiride on glycemic control in patients with typ 2 diabetes treated with insulin and metfromin

Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital. Division of internal medi0 个研究点开始时间: 2008年8月4日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
进行中(未招募)
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Typ 2 diabetes with duration = 10 years
  • BMI 24-40 kg/m2
  • Hba1c 6,0%-8,5 %
  • Ongoing treatment with insulin and Metformin since at least 1 year.
  • If a woman in fertil age is included, a safe anticonception is to be used.
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Renal impairement (creatinine levels> 130µmol/l)
  • Hepatic insufficiency (transaminases > 3 times the normal value)
  • Fasting C-peptide/plasma glucose ratio < 0,052
  • Inability to perform self monitoring of blood glucose
  • Therapy with Sulfonylureas within 1 year prior to inclusion
  • Known intolerability to glimepiride
  • Untreated proliferative retinopathy
  • Pregnancy or women in fertil age without a safe anticonception

研究者

发起方
Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital. Division of internal medi

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