Effectiveness of trauma therapy using prolonged exposure for the treatment of posttraumatic stress disorder (PTSD) in patients with comorbid psychotic disorder. A prospective, randomized, controlled trial.
Not Applicable
Recruiting
- Conditions
- F20.0Paranoid schizophrenia
- Registration Number
- DRKS00034255
- Lead Sponsor
- Medical School Hamburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
• the presence of a psychotic disorder (F20) or affective disorder with psychotic symptoms (F30) according to DSM-5
• and comorbid post-traumatic stress disorder (PTSD) according to DSM-5 (CAPS-5 score = 23)
• at least 18 years old
• Good knowledge of the German language
• Willingness to participate in randomization and trauma-focused therapy
Exclusion Criteria
• Changes in neuroleptic or antidepressant therapy within the last 4 weeks (exclusion of medication effects)
• Any substance dependence with continued use other than nicotine and/or caffeine dependence
• IQ of 70 or less
• Acute suicidality
•Pregnant women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. What influence have 16 hours of trauma therapy using Prolonged Exposure (PE) on the PTSD symptoms of patients with comorbid psychotic illness in the CAPS (Clinican – Administered PTSD Scale for DSM-5, Clinical-Administered PTSD Scale for DSM-5 , CAPS, Blake et al., 1998) between baseline measurement (T0) 6 months after the end of therapy (T2)? (Primary endpoint).
- Secondary Outcome Measures
Name Time Method