A 8 week, multi-center, randomized, double-blind, placebo-controlled clinical trial for the evaluation of the efficacy and safety of Magnolia extract on gingival health

O0 sites100 target enrollmentTBD

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

4 years ago

Study Type

Interventional Study

Sex

All

Sponsor

•1\) Adult male and female under 20 years old and under 80 years old
•2\) Those who have 10% or more of BOP (Bleeding on probing) site in all teeth and 1 or more teeth with PD (Probing Depth) of more than 3mm and 5mm or less
•3\) Those who have one or more teeth with a GI of 2 or more
•4\) Those who have at least 20 existing natural teeth (excluding implants)
•5\) Those who have consented to participate in this human application test before the start of the human application test and filled out the Informed Consent Form

•1\) Those with clinically significant cardiovascular, immune system, infectious diseases
•2\) People with mental illness such as schizophrenia, depression, drug addiction, etc.
•3\) Patients who have developed cancer within the last 5 years
•4\) Persons with a history of bleeding or disease, or taking antiplatelet drugs or anticoagulants to prevent them
•5\) Those with serious pathological findings on the soft tissues in the oral cavity
•6\) Those who need treatment such as surgery or extraction due to dental diseases that accompany them during the test period.
•7\) Patients with uncontrolled hypertension (fasting blood sugar greater than 180 mg/dl)
•8\) Patients with uncontrolled diabetes (fasting blood sugar greater than 180 mg/dl) sfsdfsdfsdfsdfsdfsdf
•9\) Those whose Creatinine is more than twice the upper limit of the laboratory
•10\) Those whose AST(GOT) or ALT(GPT) is more than 3 times the upper limit of the laboratory

Not specified