Pediatric Radiation Therapy Registry

Not yet recruiting

• Conditions: Sarcoma; Pediatric Brain Tumors

• Registration Number: NCT07129317
• Lead Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Brief Summary

The Johns Hopkins Pediatric Radiation Oncology Program is creating a registry that will capture the full 3D radiation dosimetry delivered to its pediatric patients to manage the quality of care provided, as well as to examine the long-term outcomes and toxicity of each patient. The registry will capture baseline clinical data, disease, toxicity, and quality of life outcomes. The goal is to include all pediatric patients undergoing proton therapy and photon therapy to enable future comparisons of treatment outcomes.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-08
• Study First Submitted: 2025-08-11
• Study First Submitted QC: 2025-08-12
• Last Update Submitted: 2025-08-12
• Study First Posted: 2025-08-19
• Last Update Posted: 2025-08-19
• Study Start: 2025-09-01
• Primary Completion: 2035-09
• Study Completion: 2040-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

• Treatment with either proton or photon radiation therapy.

Exclusion Criteria

• Greater than 26 years old

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall Survival	Approximately 10 years	Measured from date of diagnosis until death, obtained from medical record notes
Toxicity due to Radiation Therapy as assessed by number of patients with adverse events	Approximately 10 years	The number of patients that experience adverse events, obtained from medical record notes

Trial Locations

Locations (2)

Sibley Memorial Hospital; 🇺🇸 Washington, District of Columbia, United States

Johns Hopkins Hospital; 🇺🇸 Baltimore, Maryland, United States