Observational Prospective Study of the Predicted Value of Immature Thrombocytes Counts in Three Different Groups of Critically Ill Patients

• Conditions: Patients With Hip Fractures; Critically Ill Patients; Neutropenic Fever Patients
• Interventions: Other: Immature Platelet Fraction

• Registration Number: NCT02016859
• Lead Sponsor: Dr. Yishai Ofran

Brief Summary

Immature Platelet Fraction (IPF) is a new value in CBC blood tests Recent Studies showed that this value may be another prognostic factor in critically ill patients such as those admitted to ICU, or those with neutropenic Fever.

The purpose of the study is to check if the IPF may be used as a prognostic Factor in these patients

Detailed Description

In this study we have 3 groups of patients

* Patients admitted to ICU

* Patients admitted with neutropenic fever

* Patients admitted with hip fractures it is a prospective study, not interventional, we'll take blood samples of these patients including CBC count eith IPF and other inflammation markers such as CRP and we'll compare CRP to IPF in addition to clinical follow-up of the patient till discharge.

At the end of this study we'll compare the efficacy of IPF as a prognostic Factor in these patients

Study Timeline

• Study First Submitted: 2013-11-10
• Status Verified: 2013-12
• Study First Submitted QC: 2013-12-15
• Last Update Submitted: 2013-12-15
• Study First Posted: 2013-12-20
• Last Update Posted: 2013-12-20
• Study Start: 2014-01
• Primary Completion: 2014-05
• Study Completion: 2014-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Admission to hospital blood sample is taken between 24:00 pm till 15:00 pm

Exclusion Criteria

• blood sample is taken after 15:00 pm in the first day of admission during the week
• blood sample is taken on weekend: thursday 15:00 pm till saturday 24:00 pm

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Critically ill patients admitted to ICU	Immature Platelet Fraction	those patients who are admitted to ICU with multiorgan failure/injury
Patients of Hip's Fracture	Immature Platelet Fraction	admitted to orthopedic departement
Neutropinc Fever patients	Immature Platelet Fraction	admitted to ER, haemato-oncology or oncology

Primary Outcome Measures

Name	Time	Method
Time to recovery from sepsis or time to death	6 months	the primary outcome is the result of the patient's admission on which data analysis will be based

Secondary Outcome Measures

Name	Time	Method
Predicting value of IPF for prognosis	baeline 6 months	after the analysis of the data we'll may ba able to assess the predicting value of the IPF in predicting severity of infection and prediciting prognosis of infection in the three groups described

Trial Locations

Locations (1)

Rambam Health care campus; 🇮🇱 Haifa, Israel