Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension
- Conditions
- Hypertension, PulmonaryLung DiseasesHypertension;Pulmonary;PrimaryChronic Thromboembolic Pulmonary HypertensionVascular Diseases
- Registration Number
- NCT03388476
- Lead Sponsor
- University of Giessen
- Brief Summary
Measurement of the endtidal carbon dioxide by capnography to exclude or to ensure the diagnosis pulmonary hypertension. The aim of the study is to obtain an endtidal carbon dioxide cut-off value for the diagnostic algorithm for pulmonary hypertension as an easily measurable and cheap diagnostic tool in patients with suspicion of pulmonary hypertension.
- Detailed Description
The disease pulmonary hypertension is due to a remodeling of the lung vessels which results in a change of the exhaled air. This change is measurable with a so called capnograph. The investigators want to measure the breath from patients with and without pulmonary hypertension to detect a cut-off value for the diagnosis pulmonary hypertension.
Patients which have the probably diagnosis pulmonary hypertension and are older than 18 years are investigated. This patients will get an right heart catheterization and a measurement from their exhaled air.
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 500
Age > 18 years, suspicion of pulmonary hypertension, planned or accomplished right heart catheterization
none
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement PetCO2 At baseline Measurement PetCO2 by capnography at rest after or before a right heart catheterization, comparison of the parameter between patients with and without
- Secondary Outcome Measures
Name Time Method Establishing a cut-off At baseline Establishing a cut-off for the non-invasive diagnosing of pulmonary hypertension, which differs between patients with and without pulmonary hypertension and save patients without the disease before a dispensable invasive right heart catheterization
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Trial Locations
- Locations (1)
University Clinic Giessen and Marburg
🇩🇪Giessen, Hessen, Germany
University Clinic Giessen and Marburg🇩🇪Giessen, Hessen, Germany