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Clinical Trials/NCT04693832
NCT04693832
Completed
N/A

Trakya University, Scientific Research Projects Unit

Trakya University1 site in 1 country62 target enrollmentJanuary 1, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Oncology
Sponsor
Trakya University
Enrollment
62
Locations
1
Primary Endpoint
Adapted Rhodes Index of Nausea and Vomiting for Pediatrics
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The aim of this study was to develop an interactive mobile application and to investigate the effect of this application on the management of nausea and vomiting symptoms by using it during chemotherapy treatment.

Detailed Description

Intensive chemotherapy protocols are the most commonly used treatments in childhood cancers. While these protocols increase recovery rates, they may also cause some undesirable side effects. Nausea and vomiting are one of the most common toxic side effects associated with chemotherapy. The aim of this study was to develop an interactive mobile application and to investigate the effect of this application on the management of nausea and vomiting symptoms by using it during chemotherapy treatment. The study will be conducted with 61 children between 8-18 years of age who received chemotherapy in the Pediatric Hematology-Oncology Clinic at Trakya University Health Research and Application Center. The study was planned as a randomized controlled study. Data will be collected with the "Information Form" and "Rhodes Adapted Rhodes Nausea and Vomiting Scale for Children". The interactive mobile application will be downloaded to the phones of the experimental group and this device will be used from the first chemotherapy day to the seventh day. While the experimental group evaluates their nausea and vomiting via mobile application twice a day, every 12 hours for one week, the control group will record their nausea and vomiting experiences in the "Nausea and Vomiting Diary". While the experimental group will be able to use the mobile application which consists of diverting attention, routine control will be applied to the control group.

Registry
clinicaltrials.gov
Start Date
January 1, 2019
End Date
August 30, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Remziye Semerci

Research Assistant

Trakya University

Eligibility Criteria

Inclusion Criteria

  • Taking chemotherapy treatment,
  • To be in the age range of 8-18,
  • Volunteering to participate in research,
  • Having the first course of chemotherapy,

Exclusion Criteria

  • Having a mental problem,
  • Absence of vision, hearing and speech problems,
  • Absence of problems with the gastrointestinal system,
  • Being in the terminal period,
  • Receiving sedation therapy,

Outcomes

Primary Outcomes

Adapted Rhodes Index of Nausea and Vomiting for Pediatrics

Time Frame: Both children and their mother's assess children's frequency of the nause and vomiting twice a day, every 12 hours during one week from the first chemotherap' day to the seventh day.

The instrument consists of a series of 5 statements (rated 0-4) for each of the 6 items representing the child's perceptions of the frequency of, duration of, and distress from nausea, and the frequency of, amount of, and distress from vomiting within the past 12 hours. The ARINV includes 6 items. The first 3 items on the scale question the frequency of, amount of, and distress from vomiting during the last 12 hours and the remaining 3 items question the frequency of, duration of, and distress from nausea. The possible minimum and maximum scores to be obtained from the nausea or vomiting part of the ARINV vary between 0 and 24 per day. The possible minimum and maximum scores to be obtained from the whole ARINV vary between 0 and 48 per day.

Information Form

Time Frame: Children and parents complete this form before the study.

The information form developed by the researchers includes the socio-demographic characteristics of parents and children; mother's age, father's age, parents 'education level, parents' employment status, number of children, child's age, gender, time of diagnosis of the child, disease stage of the child, types of treatment received, the number of cycles. It consists of 20 questions.

Study Sites (1)

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