Increased brain iron deposition in the basial ganglia is associated with cognitive and motor dysfunction in type 2 diabetes

Shandong Provincial Hospital Affiliated to Shandong First Medical University0 个研究点目标入组 535 人开始时间: 2023年11月7日最近更新: 2023年11月20日

适应症

试验速览

暂无简介。

•The inclusion criteria for all subjects are:
•1. Age from 40 to 70 years old
•2. Right-handedness
•Healthy controls:
•1. No history of diabetes and glycated hemoglobin (HbA1c) level between 4 and 6%
•2. No history of severe mental or neurologic diseases
•3. No history of head trauma, surgery, or tumors
•4. No alcohol or drug abuse.
•1. All patients met the diagnostic criteria of type 2 diabetes of the 2023 American Diabetes Association, and the diagnosis of diabetic peripheral neuropathy conformed to the Toronto consensus criteria.
•2. Diabetic peripheral neuropathy patients had at least one type of neuropathy characterized by numbness, prickling, and burning pain primarily in the extremities, and the signs included weakening or disappearance of ankle reflexes or symmetric decrease of distal sensory symmetry.

发起方

Shandong Provincial Hospital Affiliated to Shandong First Medical University