REsting enERgy Expenditure in mechanically ventilated patients in the ICU and during COnValescence: a prospective cohort study
Completed
- Conditions
- Critical Illness
- Registration Number
- NL-OMON23231
- Lead Sponsor
- A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Admitted to the ICU of the ZGV hospital aged 18 and above, endotracheally mechanically ventilated, expected to be in ICU for more than 48 hours, expected to be in the general ward after ICU discharge.
Exclusion Criteria
Fraction of inspired oxygen >0.7, PEEP>12 cm H2O, air leaks through tubes/cuffs and/or chest drains, pneumothorax, tracheaoesophageal fistulae or subcutaneous emphysema, unavailability of the QNRG metabolic monitor, peritoneal or hemodialysis or hemofiltration up to 4 hours before/after a session or during CRRT, expected to be transferred.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare resting energy expenditure (REE), measured by indirect calorimetry, during ICU stay and post-ICU hospital stay.
- Secondary Outcome Measures
Name Time Method To compare VCO2, VO2 and respiratory quotient (RQ), measured by the QNRG indirect calorimeter during ICU and post-ICU hospital stay. To compare REE measured by QNRG with the calculated REE using the VCO2-method and several other predictive equations. To associate REE and physical performance using the CPAx-score at the ICU- and hospital discharge.