Investigating the effect of midodrine in preventing septic shock in childre

Phase 3

Recruiting

• Conditions: R65.20; Preventing septic shock in children with severe sepsis.; Severe sepsis without septic shock

• Registration Number: IRCT20120520009801N14
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-07-22

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Age more than 1 month and less than 10 years admitted to PICU with severe sepsis
Obtain informed consent from the patient's parents
Normal SVRI (1200 - 1600)

Exclusion Criteria

Hypertention (mean arterial pressure upper than 80 mmHg)
History of Pheochromocytoma
Urinary retention
Thyrotoxicosis
History of taking Midodrine
Impairment of liver function (Child-Pugh class C)
Very ill patient ( ie. history of cardiopulmonary resuscitation)
Having congenital haert disease

Study & Design

• Study Type: interventional
• Study Design: Not specified