Social cognition following deep brain stimulation of the medial forebrain bundle in treatment-resistant depressio

Not Applicable

• Conditions: F33.2; Recurrent depressive disorder, current episode severe without psychotic symptoms

• Registration Number: DRKS00019092
• Lead Sponsor: Department für Psychische ErkrankungenKlinik für Psychiatrie und PsychotherapieUniklinik FreiburgAbteilung für Interventionelle Biologische Psychiatrie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-13
• Study Completion: 2021-02-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Inclusion criteria for patients with treatment-resistant depression are described in the main study investigating the efficacy of deep brain stimulation in treatment-resistant depression (registered at clinicaltrials.gov). For healthy controls, no inclusion criteria are defined. Healthy controls are matched.

Exclusion Criteria

Exclusion criteria for patients with treatment-resistant depression are described in the main study investigating the efficacy of deep brain stimulation in treatment-resistant depression (registered at clinicaltrials.gov). For healthy controls, no exclusion criteria are defined. Healthy controls are matched.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Emotion recognition (EmoDetect) and Theory of Mind (ToM) ability (EmpaToM) at baseline, comparision of patients with treatment-resistant depression and healthy controls.

Secondary Outcome Measures

Name	Time	Method
Change of emotion recognition and Theory of Mind ability after four months of treatment with active stimulation.