Mood treatment with antidepressants or running

Completed

• Conditions: angststoornissen; major depressive disorder and anxiety disorder; depression and anxiety; 10027946

• Registration Number: NL-OMON39034
• Lead Sponsor: GGZ inGeest (Amsterdam)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 270

Inclusion Criteria

Clients (aged 18-65) can take part if they meet the DSM-IV criteria for a current major depressive disorder (MDD) and/ or current anxiety disorder.
Healthy persons can take part if they are aged 18-65 years.

Exclusion Criteria

Patient-sample: Current use of antidepressants (antidepressants have to be eliminated for at least 4 weeks for participation of this study), current use of psychotropic medication, except for the use of benzodiazepine for which dosage has to be constant, ongoing participation in regular (>1/week) exercise, primary severe, clinically diagnosed psychiatric diagnosis other than depression or anxiety (bipolar disorder, psychosis, addictive disorder), evidence of acute suicidal risk, medical contra-indications to exercise or antidepressants as confirmed by a physician ;Control-group: lifetime psychiatric disorder, lifetime treatment for psychological symptoms, ongoing participation in regular (>1/week) exercise, medical contra-indications to exercise or antidepressants as confirmed by a physician

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Is SSRI treatment or exercise therapy in depression and/or anxiety comparable<br /><br>for depression and anxiety symptomatology and physiological stress?</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secundary outcome: reduced cellulair aging and metabolic stress after<br /><br>depression and anxiety treatment and change in brain activity after treatment. </p><br>