Optimal Timing of Coronary Intervention in Unstable Angina 2

Completed

• Conditions: heart attack; myocardial infarction; 10011082

• Registration Number: NL-OMON36977
• Lead Sponsor: Cardiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 350

Inclusion Criteria

- Age > 21 years
- Typical chest pain for angina pectoris lasting at least 10 minutes, within
the
last 24 hours
- No contra-indication to PCI
- And at least one of the following criteria:
1. 1 mm of horizontal or downsloping ST depression
2. Dynamic ST- or T- wave changes > 1 mm in two contiguous leads
3. Elevated hs troponin (>1xULN)
4. Known coronary artery disease
5. Two of following risk factors: DM, known hypertension, current smoking,
family history for ischemic heart disease, hypercholesterolemia, peripheral
artery disease, age over 60 years.

Exclusion Criteria

- Acute ST myocardial infarction
- Refractory angina
- Severe heart failure
- Life-threatening ventricular arrhythmias
- Haemodynamic instability
- Contraindication for the use of Ticagrelor
- Participation in another study
- Use of oral anticoagulants

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint will be:<br /><br>Size of MI during initial hospitalization as measured by the AUC of CK-MB.</p><br>