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D-dimer Assay for the Exclusion of Intra-atrial Thrombus Risk Before Ablation of Atrial Fibrillation

Not Applicable
Completed
Conditions
Atrial Fibrillation
Registration Number
NCT02199080
Lead Sponsor
Groupe Hospitalier de la Rochelle Ré Aunis
Brief Summary

The purpose of this study is to determine whether D-dimer dosage allow to exclude risk of intraatrial thrombus before performing an ablation of atrial fibrillation

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2506
Inclusion Criteria
  • Age> 18 years.
  • Patients hospitalized for ablation of atrial fibrillation or symptomatic left flutter
  • Patient informed of the study
Exclusion Criteria
  • Age <18 years.
  • Patients under guardianship
  • Pregnant woman
  • Contraindication to transesophageal echocardiography
  • transesophageal echocardiography made in another center as the center of ablation
  • Refusal of the patient to participate in the study
  • Patient participating in another interventional study in which an intervention related to biomedical research is performed before the transesophageal echocardiography

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Number of Patients With Atrial Thrombus Diagnosed by Transoesophageal Ultrasoundup to 48 hours before ablation
Secondary Outcome Measures
NameTimeMethod
Risk Factors48 hours before ablation

variables related to the presence of atrial thrombus

Atrial Thrombus Exclusion (ATE) Score48 hours before ablation

The following thromboembolic risk factors mark 1 point if present in patient:

* hypertension = 1 point

* cardiac insufficiency = 1 point

* history of stoke = 1 point

* d-dimer level \>270ng/mL = 1 point The sum corresponds to the ATE score

CHADS2 Score48 hours before ablation

CHADS2 score (congestive heart failure=1, hypertension=1, diabetes mellitus=1, history of stroke or transient ischemic attack=1, and age under 75=1)

Trial Locations

Locations (37)

Service de cardiologie, CH de la Région d'Annecy

🇫🇷

Annecy, France

Centre Hospitalier d' Auxerre

🇫🇷

Auxerre, France

Service de cardiologie, CH Avignon

🇫🇷

Avignon, France

Clinique La Fourcade

🇫🇷

Bayonne, France

Service de cardiologie, CHU Bordeaux

🇫🇷

Bordeaux, France

Service de cardiologie, CHU Brest

🇫🇷

Brest, France

Service de cardiologie, CHU Caen

🇫🇷

Caen, France

Service de cardiologie, CHU Clermont Ferrand

🇫🇷

Clermont Ferrand, France

Service de cardiologie, AP Hôpital Henri Mondor

🇫🇷

Créteil, France

Service de cardiologie, CHU Dijon

🇫🇷

Dijon, France

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Service de cardiologie, CH de la Région d'Annecy
🇫🇷Annecy, France

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