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Clinical Trials/NCT06465784
NCT06465784
Completed
Phase 4

Comparison Between Retrograde and Antegrade Ureteroscopic Laser Lithotripsy for Management of Medium Sized Proximal Ureteral Stones: A Randomized Prospective Study

Mahmoud Helmy El saeed Hussein1 site in 1 country70 target enrollmentMarch 1, 2023
ConditionsUreteric Stone

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Ureteric Stone
Sponsor
Mahmoud Helmy El saeed Hussein
Enrollment
70
Locations
1
Primary Endpoint
Stone free rate
Status
Completed
Last Updated
last year

Overview

Brief Summary

Objectives: To present the outcomes of retrograde and antegrade ureteroscopic laser lithotripsy in the treatment of proximal ureteral stones ranging in size from 10 to 20 millimeters in diameter.

Patients and methods: From March 2023 to December 2023, 70 patients were included in this prospective randomized double-arm interventional study. Patients were divided into two groups: Group 1: (35 patients) had semi-rigid retrograde ureteroscopic laser lithotripsy and group 2: (35 patients) had semi-rigid antegrade ureteroscopic laser lithotripsy.

Detailed Description

The present study was conducted in Al-Azhar University Hospital (Damietta branch), urology department,at the period from March 2023 to December 2023. Seventy patients with symptomatic proximal medium sized ureteric stones were classified in two groups Retrograde Uretroscopic Laser Lithotripsy (group 1) and Antegrade Ureteroscopic Laser Lithotripsy (group 2) . The preoperative-(patient- and stone-related), intraoperative- and postoperative- related parameters that might influence the perioperative course and short-term clinical outcomes were evaluated.

Registry
clinicaltrials.gov
Start Date
March 1, 2023
End Date
December 31, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Mahmoud Helmy El saeed Hussein
Responsible Party
Sponsor Investigator
Principal Investigator

Mahmoud Helmy El saeed Hussein

Professor

Al-Azhar University

Eligibility Criteria

Inclusion Criteria

  • Patients with medium-sized proximal ureteral stones (10-20 mm) situated between the ureteropelvic junction and the top edge of the L5 vertebral body; age 18-65 years

Exclusion Criteria

  • Pregnancy, bleeding disorders, morbid obesity (BMI \> 35), patients with stenosis of the ureter, history of previous surgery on the ipsilateral ureter, patients with a simultaneous kidney stone requiring surgery, and patients with an active urinary tract infection

Outcomes

Primary Outcomes

Stone free rate

Time Frame: Direct after intervention

number of patients reported complete clearance of stones after intervention

Study Sites (1)

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