The effect of static magnetic stimulation on the cortical excitability of patients with a presumed diagnosis of motor neuron disease
Not Applicable
- Conditions
- G12.2Motor neuron disease
- Registration Number
- DRKS00025294
- Lead Sponsor
- niversitätsklinikum Göttingen; Klinik für Anästhesiologie und Klinik für Neurologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
Age >17 years of age; Diagnosis made within the last 3 months; duration of symptoms less than 2 years
Exclusion Criteria
General:
- uncontrolled systemic disease
- legal custody
- pregnancy
- nursing period
- drug abuse and/or excessive use of alcohol within the last 6 months
Regarding TMS
- Epilepsy
- Craniocervical metal implants
- Electromagnetic implants such as pacemakers
- Certain medication (neuroleptics, antidepressives, benzodiazepines, antiepileptics)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method What: Amplitude and latency of the EMG of a single hand muscle;<br><br>When: After application of a transcranial static magnet;<br><br>How: Measurements with transcranial dynamic magnetic stimulation
- Secondary Outcome Measures
Name Time Method What: Acceptance of the technique by patients;<br><br>When: After application of the static magnetic stimulation;<br><br>How: Measurement by a questionaire