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Clinical Trials/NCT06224933
NCT06224933
Recruiting
Not Applicable

Augmented Reality Real-Time Guidance for MRI-Guided Interventions

Children's National Research Institute1 site in 1 country25 target enrollmentFebruary 6, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Children's National Research Institute
Enrollment
25
Locations
1
Primary Endpoint
Safety of using the augmented reality needle guidance system will be evaluated through assessment of procedure related adverse events that occur within 7 days of the procedure.
Status
Recruiting
Last Updated
7 months ago

Overview

Brief Summary

The purpose of this study is to determine feasibility and safety of using an augmented reality system in patients undergoing MRI-Guided needle procedures.

Detailed Description

This pilot clinical study is designed to evaluate the feasibility of using a needle guidance system during MRI-guided procedures in up to 12 patients. The MRI-compatible needle guidance system was developed under an NIH funded SBIR Phase II grant. This system has been evaluated by our Interventional Radiology team in phantom, volunteer, and cadaver studies which showed potential benefit of use in patients. Inclusion of the needle guidance system will not change the standard of care or substantively affect procedural technique as currently performed. This system provides the operator with an augmented reality (AR) display to better visualize the needle entry point and trajectory as it is inserted toward the target. This additional information could improve needle placement accuracy and shorten procedural time.

Registry
clinicaltrials.gov
Start Date
February 6, 2024
End Date
May 31, 2026
Last Updated
7 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Children's National Research Institute
Responsible Party
Principal Investigator
Principal Investigator

Karun Sharma MD

Director of Interventional Radiology

Children's National Research Institute

Eligibility Criteria

Inclusion Criteria

  • Provision of signed and dated informed consent form
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Male or female, ages 3 to 21
  • Patient referred to Interventional Radiology for image-guided needle injection, aspiration, or biopsy.

Exclusion Criteria

  • Patients who are unable to give informed consent themselves or through their parents.
  • Patients under 3 years of age
  • Patients over 300 pounds.
  • Patients who are claustrophobic and unable to tolerate MRI-guided procedure.
  • Contraindications to MRI such as MR-unsafe implants.

Outcomes

Primary Outcomes

Safety of using the augmented reality needle guidance system will be evaluated through assessment of procedure related adverse events that occur within 7 days of the procedure.

Time Frame: 7 days

Feasibility is measured by successful completion of greater than 80% of cases using the augmented reality needle guidance system.

Time Frame: 1 day

Secondary Outcomes

  • Procedure time(1 day)
  • Number of MRI scans(1 day)
  • Clinical impressions of the system use and utility(1 Day)

Study Sites (1)

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