Antibiotics Management of Septic Neutropenic Patients in the Intensive Care Unit

Completed

• Conditions: Neutropenia, Febrile

• Registration Number: NCT03217721
• Lead Sponsor: University Hospital, Brest

Brief Summary

Neutropenia, defined by an absolute count of polymorphonuclear neutrophils less than \<1500/mm3, exposes patients to infectious complications that can lead to sepsis or septic shock. The mortality risk is higher risk. The recommendations published in 2016 were formulated to homogenize the clinical practices to improve the survival.

Detailed Description

We evaluate the adequacy antibiotics prescriptions in febrile neutropenia with suspected infection and evaluate factors influencing adequacy therapy and mortality consequence.

Study Timeline

• Study Start: 2017-06-19
• Status Verified: 2017-07
• Study First Submitted: 2017-07-05
• Study First Submitted QC: 2017-07-12
• Study First Posted: 2017-07-14
• Primary Completion: 2017-09-19
• Study Completion: 2017-09-19
• Last Update Submitted: 2024-08-09
• Last Update Posted: 2024-08-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

• Sepsis or septic shock at admission or during the stay

Exclusion Criteria

• Minor
• Pregnancy
• Opposition

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of adequate antibiotic prescription	Through study completion, an average of 1 month	Proportion of adequate antibiotic prescription

Secondary Outcome Measures

Name	Time	Method
Mortality of all causes	ICU, hospital and 28-day mortality	Mortality of all causes

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France