To Compare Anaesthetic Effect of intrathecal 1% 2-Chloroprocaine versus ropivacaine 0.5% with Fentanyl in Urological Surgeries.

Not yet recruiting

• Conditions: Disorder of urinary system, unspecified,

• Registration Number: CTRI/2021/11/037980
• Lead Sponsor: Department of Anaesthesiology SMS Medical College and Attached Group of Hospitals Jaipur

Brief Summary

Intrathecal chloroprocaine can be used as an alternative to long acting local anesthetics such as ropivacaine for urological surgeries requiring short duration and early ambulation with minimum side effects. As we observed in this study that the intrathecal 1% 2-chloroprocaine with fentanyl provides adequate motor blockade and analgesia for day care urological surgeries while 0.5 % ropivacaine with fentanyl provides a greater duration of sensory and motor blockade than chloroprocaine. Furthermore, fentanyl as an adjuvant to both ropivacaine and chloroprocaine enhances the duration of analgesia and stabilizes hemodynamic variables.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-20
• Last Update Posted: 2022-08-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1.Patients willing to give consent to participate in the study.
• 2.Patients posted for urological surgeries belonging to ASA grade I and II.
• 3.Age between 18 and 55 years.
• 4.Weight between 50 and 75 kg and height between 150 and 180 cms.

Exclusion Criteria

• 1.Patients with skin infection at local site.
• 2.Patients with severe hypovolemia, severe MS, blood coagulopathies.
• 4.Patients allergic to drugs used for study.
• 5.Failure of spinal anaesthesia, cases in which general anaesthesia will be required.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the difference in mean onset time and duration of motor block in both groups.	To compare the difference in mean onset time and duration of motor block in both groups.

Secondary Outcome Measures

Name	Time	Method
1.To compare the in degree of motor and sensory block in both groups.	2.To determine difference in change in hemodynamic variables for baseline to 5,10,15,20 mins upto 4 hours post spinal period.

Trial Locations

Locations (1)

S.M.S. Medical College and Attached group of Hospitals; 🇮🇳 Jaipur, RAJASTHAN, India

S.M.S. Medical College and Attached group of Hospitals

🇮🇳Jaipur, RAJASTHAN, India

Dr Aayushi Dadhich

Principal investigator

9414870228

aayushidadhicha@gmail.com