The effect of Omega 3 supplementation on oxidative stress & the gene expression of sestrin 2 enzyme & Nrf2 factor in diabetic patient type 2

Iran University of Medical Sciences0 个研究点目标入组 70 人开始时间: 待定最近更新: 2020年2月24日

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•Diabetic patients with diabetes duration more than one year.
•Diabetic patient in both genders, men 36-65 years old and women from 30 years old upto before menopause.
•BMI in the range of 25-40 kg/m2.
•Literateness (for recording 3-day meal)
•Willingness to maintain weight during the study.
•Willingness to maintain routine activities and current lifestyle during the study.
•Willingness to participate in the study

•pregnancy and lactation
•Consumption of omega-3 supplement in the last three months.
•having chronic renal, hepatic, enteric, haematic disorders, microalbuminuria, retinopathy, neuropathy, hypo/hyperthyroidism, cardiac disease, type 1 diabetes according to patient declaration and medical history.
•Treatmetn with orlistat, cybotramin, insulin, thiazolidinediones, non-steroidical anti-inflammatory drugs
•Using Combined oral contraceptive pills
•Using dietary supplements, vitamin supplements, and herbal supplements at least 2 weeks before intervention
•Changing dose or type of anti-diabetic drug
•Occurrence of any inflammatory disease which requires using anti-inflammation drugs.
•Unwillingness to continue participation.
•Using less than 90 percent of the omega 3 supplement.
•Appearance of any allergic reactions to omega-3.

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