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Clinical Trials/NCT03792880
NCT03792880
Completed
Not Applicable

Global Self-management Telematic Support for Patients With Obstructive Sleep Apnea-hypopnea Syndrome, CPAP Treatment and Forecast of Poor Compliance.

Virgen del Puerto Hospital2 sites in 1 country60 target enrollmentJune 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obstructive Sleep Apnea
Sponsor
Virgen del Puerto Hospital
Enrollment
60
Locations
2
Primary Endpoint
Patients with a good CPAP compliance
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This clinical trial compares the usual follow-up to a program of telematic control and self-management in a group of patients with severe obstructive sleep apnea-hypopnea syndrome (OSAHS), few symptoms and treated with continuous positive airway pressure (CPAP). The objective of the intervention is to achieve a CPAP compliance of ≥4 hours per day in at least 90% of the subjects.

Detailed Description

Low CPAP compliance in OSAHS could mean that its possible cardiovascular benefits are not achieved. Telemedicine can be an effective tool to increase CPAP compliance with low cost. The researchers propose to carry out a randomized study about patients with severe OSAHS and few symptoms, who are expected to have low CPAP compliance. The main objective is to evaluate if a telematic control and self-management program can increase the compliance with CPAP treatment compared to conventional follow-up, getting at least 90% of patients to use CPAP ≥ 4 hours per day. Sixty patients from the Pneumology departments of two hospitals, diagnosed with severe OSAHS and with few symptoms (Epworth Sleepiness Scale ≤10) will be randomized to two follow-up groups, telematic and conventional, for 6 months. Patients in the intervention group (telematic monitoring) will collect variables related to symptoms of sleep apnea and side effects of CPAP treatment, using their own smartphone or a tablet provided during the study if they prefer. Other variables as the hours per day of CPAP use, leaks and residual apnea-hypopnea index (AHI) will be transmitted daily and automatically from latest generation CPAP. All information will be processed and each variable will generate alarms and instructions for each patient, allowing the self-management and an early solution of the possible problems related to the treatment. Alarms may also be generated in the database if the professional intervention is necessary. In addition, before starting CPAP treatment and after six months of treatment, patients will be monitored during a week with a watch-like device. Variables related to circadian rhythm will be collected and analyzed to know the effect of CPAP treatment in both groups (control and intervention groups).

Registry
clinicaltrials.gov
Start Date
June 1, 2019
End Date
December 28, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Virgen del Puerto Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with a recent diagnostic of OSAHS with AHI≥ 30 and indication of CPAP.
  • Age≥ 18 years
  • Few symptoms, so that, without hypersomnolence (Epworth sleepiness scale ≤ 10)
  • Absence of clinic suspect or confirmation of other sleep pathology
  • With interest in the use of new technologies

Exclusion Criteria

  • Nasal obstruction that prevents the use of CPAP
  • Psycho-physical inability to complete questionnaires and carry out the program
  • Patients undergoing uvulopalatopharyngoplasty
  • Cheyne-Stoke syndrome
  • Pregnancy
  • Absence of informed consent
  • Shift work in the last 3 months and transmeridian trips in the last month.

Outcomes

Primary Outcomes

Patients with a good CPAP compliance

Time Frame: Six months

Percentage of patients with a CPAP compliance ≥4 hours per day. The main objective is to assess if a self-management and telematic control program can increase CPAP compliance getting at least 90% of patients using CPAP ≥4 hours per day.

Secondary Outcomes

  • Efficacy of the treatment according to the change in sleepiness(Six months)
  • Efficacy of the treatment according to the change in the frequency of the snoring.(Six months)
  • Effect of the age on the treatment efficacy(Six months)
  • Effect of the gender on the treatment efficacy(Six months)
  • Dropout(Six months)
  • Side effects(Six months)
  • Efficacy of the treatment according to the change in the frequency of the witnessed apneas(Six months)
  • Effect of the treatment in the quality of sleep using the change in the rhythm of exposure to light(Six months)
  • Effect of the use of humidifier on the treatment efficacy(Six months)
  • Effect of the presence of side effects on the treatment efficacy(Six months)
  • CPAP compliance(Six months)
  • Efficacy of the treatment according to the change in the frequency of the refreshing sleep(Six months)
  • Effect of the presence of a couple on the treatment efficacy.(Six months)
  • Cost-effectiveness analysis(Six months)
  • Presence of air leak and residual AHI(Six months)
  • Effect of the treatment in the quality of sleep using the change in the rhythm of the distal skin temperature.(Six months)
  • Effect of the treatment in the quality of sleep using the change in the rhythm of activity.(Six months)
  • Effect of the treatment in the quality of sleep using the change in the result of an integrated analysis of the distal skin temperature, activity and position records.(Six months)
  • Change of quality of life using the change in the EuroQol-5 dimensions-3 levels questionnaire.(Six months)
  • Effect of the CPAP pressure on the treatment efficacy(Six months)
  • Effect of the type of mask on the treatment efficacy(Six months)

Study Sites (2)

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