Prevalence, Risk Factors and Clinical Outcomes of Sepsis Induced Myocardial Dysfunction (SIMD): A Prospective Study in King Chulalongkorn Memorial Hospital, Thailand

Recruiting

• Conditions: Sepsis induced myocardial dysfunction; Sepsis induced myocardial dysfunction, septic shock, sepsis, echocardiogram

• Registration Number: TCTR20221112004
• Lead Sponsor: Faculty of Medicine, Chulalongkorn university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-12
• Study Completion: 2022-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

Compared group
1. Admitted patients who were diagnosed as sepsis (sepsis, severe sepsis, septic shock)
2. Sepsis patients who were diagnosed as sepsis induced myocardial dysfunction
3. Aged 20-100 years during sepsis

Controlled group
1. Admitted patients who were diagnosed as sepsis (sepsis, severe sepsis, septic shock)
2. Aged 20-100 years during sepsis

Exclusion Criteria

1. Not fulfill criteria of sepsis from Sepsis-3 definition
2. Prior history of reduced left ventricular ejection fraction (< 40%)
3. Concurrent acute myocardial infarction
4. Echocardiogram shows stress induced cardiomyopathy
5. History of prior medications or drugs which can cause myocardial dysfunction such as doxorubicin, trastuzumab, amphetamine
6. Cardiac arrest in admission

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of SIMD At time of recruitment Percentage

Secondary Outcome Measures

Name	Time	Method
Risk factors At time of recruitment Odd ratio,Clinical outcome; 28-day mortality 28 days after recruitment Odd ratio