Investigation of the Relationship Between Fatigue and Physical Activity Level in Patients With Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Gazi University
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Fatigue
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Multiple sclerosis (MS) is a chronic, progressive and unpredictable disease of the central nervous system. In MS, various loss of strength, balance and gait disturbances arise in the central nervous system due to sensory and/or motor neuron degeneration. These disorders lead to limitations in individual activities and participation.
Fatigue is as reported one of the most common first three symptoms among patients with MS and affects up to 80% of the patients. Fatigue is defined as the lack of physical and/or mental energy. Sometimes fatigue can reduce the quality of life by leaving other disorders behind. The most important effect of fatigue is that individuals reduce their physical activity levels. This can lead to the inactivity-related secondary problems being added to the findings of the disease. So the physical capacities of individuals may gradually decrease.
In the literature, there are many studies showing that the level of physical activity of individuals with MS is lower than in healthy individuals. When the investigators analyze the studies that investigate the relation between fatigue and physical activity levels, it is seen that there is the single study about this subject in the literature.
As a result, additional studies are needed to investigate the level of physical activity and the factors affecting it in individuals with MS. Therefore, the investigators planned this study to investigate the relationship between fatigue and physical activity levels in patients with MS.
Detailed Description
According to sample size calculation 37 diagnosed Multiple Sclerosis patients and 37 healthy individuals will be included.The demographic characteristics of the participants initially will be taken and Expanded Disability Status Scale score of those of MS will be recorded. Then, fatigue severity and perception, physical activity level, balance, peripheral muscle strength, functional mobility, functional exercise capacity will be evaluated. Primary outcomes are fatigue and physical activity level; secondary outcomes are balance, peripheral muscle strength, functional mobility, functional exercise capacity.
Investigators
Kader Eldemir
Research Asisstant
Gazi University
Eligibility Criteria
Inclusion Criteria
- •18-65 years of age
- •Having a diagnosis of "Multiple Sclerosis" by a specialist physician
- •Relapse free in the last 3 mounts
- •Having an ambulatory status (Expanded Disability Status Scale score ≤ 6 )
- •No diagnosis of depression
Exclusion Criteria
- •Any cardiovascular, orthopedic, visual, hearing and perception problems that may affect the results of the research
Outcomes
Primary Outcomes
Fatigue
Time Frame: Eight minutes
Fatigue Impact Scale
Fatigue severity
Time Frame: Five minutes
Fatigue Severity Scale
Physical activity behavior
Time Frame: Three days
Evaluated using an ActiGraph (GT3X+)
Physical activity
Time Frame: Five minutes
International Physical Activity Questionnaire
Secondary Outcomes
- Balance(Fifteen minutes)
- Functional Mobility(Two minutes)
- Muscle strength(Fifteen minutes)
- Functional exercise capacity(Fifteen minutes)