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Feasibility of Whole Body Irradiation for Refractory/Relapsed (treatment resistant) lymphomas

Phase 1
Conditions
Health Condition 1: C969- Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecifiedHealth Condition 2: null- Patients with proven diagnosis of relapsed/refractory lymphoma
Registration Number
CTRI/2018/07/015113
Lead Sponsor
Tata Memorial Centre
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.all cases of relapsed / refractory Hodgkinâ??s or Non-Hodgkinâ??s lymphoma

2. aged less than 70 yrs, have failed standard first line therapy and have been deemed unfit for ASCT and/or Aggressive salvage regimens due to poor general condition, unable to afford chemotherapy and/or ASCT, found unfit for any form of chemotherapy or unwilling for chemotherapy; but amenable to follow up with

acceptable laboratory parameters and informed consent taken.

Most of these cases would otherwise be deemed palliative/best supportive care.

Exclusion Criteria

1. KPS score of less than 60

2. lab parameters (Hbless than 8gm/dl, Platelets less than 50,000/ml,

ANC less than 1000/mm3) 3.

unwilling for RT and RT contraindications such as hypersensitivity and collagen vascular disorders.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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