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Diet and Physical Activity Program in Colorectal Cancer Survivor: a Randomized Controlled Trial

Not Applicable
Conditions
Colorectal Cancer
Interventions
Behavioral: Group D
Registration Number
NCT06194786
Lead Sponsor
Habib Bourguiba University Hospital
Brief Summary

Colorectal cancers (CRC) represent the 1st digestive cancer and the 3rd cancer in the world. The World Cancer Research Fund summarized evidence from observational studies and concluded that low dietary fiber, and high red and processed meat (RPM) intakes were associated with higher risk of (CRC), whilst physical activity (PA) protected against developing colon cancer.

Post-treatment management is essential for improving the health and quality of life of colorectal cancer (CRC) survivors. The number of cancer survivors is continually increasing, which is causing a corresponding growth in the need for effective post- treatment management programs. To date, there is insufficient information available from the published literature as to the most effective way in promoting lifestyle changes in CRC survivors. Moreover, none of these interventions have been conducted in an African population. We aim to assess whether the proposed program may effectively modify the targeted behaviors, to evaluate whether the dietary and PA interventions of the "Moving Bright, Eating Smart" program are effective in reducing the consumption of red and processed meat (RPM) and refined grain (RG), increasing the physical activity (PA) levels in north African (Libyan and Tunisian) adult colorectal cancer (CRC) survivors and to assess the efficacy of behavioral interventions on cancer outcomes (overall survival, disease free survival).

Detailed Description

Not available

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
260
Inclusion Criteria
  • Histologically proven colorectal adenocarcinoma patients above the age of 18 years within one year of completion of main cancer treatment who are able to provide informed consent.
Exclusion Criteria
  • Colorectal cancer patients who have persistent or recurrent disease at the time of the recruitment, are receiving cancer treatment, have known contraindication to physical activity, have psychiatric disease.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Group BGroup DDietary only
Group AGroup DDietary and physical activity
Group CGroup DPhysical activity only
Primary Outcome Measures
NameTimeMethod
physical activity target-cancer outcome0-6-12-18-24 months

accelerometer or stopwatch or phone timer

Dietary target-red meat0-6-12-18-24 months

food frequency questionnaire

Secondary Outcome Measures
NameTimeMethod
Disease free survival12-24 months

time between randomization and progression

overall survival12-2 months

time between randomization and date of last news

Trial Locations

Locations (1)

Wala Ben Kridis

🇹🇳

Sfax, Tunisia

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