Clinical study over a period of at least 6 months to an individualized strength and endurance training in COPD patients in Marburger
Not Applicable
Recruiting
- Conditions
- J44.8Other specified chronic obstructive pulmonary disease
- Registration Number
- DRKS00006842
- Lead Sponsor
- Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University Marburg, Germany, Member of the German Center for Lung Research (DZL)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Patients diagnosed with COPD, patients of stage I - IV or AD (according to GOLD classification)
Exclusion Criteria
Regard to acute pathological cardiac events (e.g. heart attack), comorbidities such as heart failure (NYHA III and IV), congestive heart failure, high blood pressure (> 220/120 mmHg), severe mental illness, cognitive impairments, limitations of the musculoskeletal system, which make a training impossible, neurological diseases that affect the training and implementation, acute exacerbations, acute inflammation / infection
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Exercise capacity as measured by 6-minute walk test before and after 3- and 6-month treatment phase for the individualized training group and before and after 3 months in the control group
- Secondary Outcome Measures
Name Time Method Following parameters will be measured in the individualized training group at baseline, 3- and 6-month after treatment phase and before the start and after 3 months in the control group:<br>1. quality of life (SGRQ, CAT score, HADS)<br>2. Physical fitness (endurance performance (bicycle ergometer tests))<br>3. lung function (Spirometire)<br>4. Systemic inflammation (serum concentration of inflammatory markers)<br>5. breath condensate (EBC)<br>6. laboratory parameters (muscular function)<br>7. left/right ventricular function<br>8. bone turnover markers