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Clinical Trials/NCT06450457
NCT06450457
Completed
Not Applicable

Effects of High Intensity Stepping Training on Gait in Patients With Ataxia

The University of Texas Health Science Center, Houston1 site in 1 country4 target enrollmentMarch 26, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cerebellar Ataxia
Sponsor
The University of Texas Health Science Center, Houston
Enrollment
4
Locations
1
Primary Endpoint
Walking Speed in Meters Per Second as Assessed by the 10 Meter Walk Test(10MWT)
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to examine the effects of high intensity stepping training on gait recovery, including walking speed and endurance, in patients with cerebellar ataxia. The hypothesis is that there will be a significant improvement in gait outcome measures (6 Minute Walk Test and 10 Meter Walk Test) in patients who receive high-intensity stepping training during physical therapy.

Registry
clinicaltrials.gov
Start Date
March 26, 2024
End Date
May 10, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Kaitlin Benjamin

Student, Principal Investigator

The University of Texas Health Science Center, Houston

Eligibility Criteria

Inclusion Criteria

  • diagnosis of ataxia
  • admitted to The Institute for Rehabilitation and Research (TIRR) Texas Medical Center (TMC) Inpatient or TIRR Kirby Glenn Outpatient
  • pathology that primarily affects the brain/cerebellum, including degenerative diseases, stroke, traumatic brain injury (TBI), posterior fossa tumor, and multiple sclerosis (MS)
  • ambulatory at initial evaluation or will have functional ambulation goals at initial evaluation (as noted by 10 meter walk test and 6 minute walk test measures documented as 0)
  • chronicity of injury will be of at least 1 month or greater

Exclusion Criteria

  • diagnoses that may have cerebellar involvement but without cerebellar ataxia as a principal impairment such as autism, down syndrome, schizophrenia, etc
  • non ambulatory or who are not able to participate in high intensity stepping training due to cardiac involvement (such as cardiac rehabilitation parameters) or due to orthopedic limitations (such as weight bearing parameters)

Outcomes

Primary Outcomes

Walking Speed in Meters Per Second as Assessed by the 10 Meter Walk Test(10MWT)

Time Frame: Baseline, 3 weeks

Participant is asked to walk a distance of 10 meters and the speed is measured by dividing the distance covered by the time taken.

Distance Walked in Feet as Assessed by the the Six Minute Walking Test (6MWT)

Time Frame: Baseline, 3 weeks

Participants will be asked to walk as far as possible for 6 minutes. Longer distance walked shows better outcome.

Secondary Outcomes

  • Ataxia as Assessed by the Scale for the Assessment and Rating of Ataxia (SARA)(Baseline, 3 weeks)
  • Ability to Balance as Assessed by the Berg Balance Scale (BBS)(Baseline, 3 weeks)

Study Sites (1)

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