A Pilot Study of Continuous Negative Pressure (CNEP) In Bronchiolitis

Not Applicable

Terminated

• Conditions: Bronchiolitis; Respiratory

• Registration Number: ISRCTN53796751
• Lead Sponsor: niversity Hospital of North Staffordshire (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2004-03-05
• Study Completion: 2004-12-31
• Last Update Posted: 24 August 2021

Recruitment & Eligibility

• Status: Stopped
• Sex: Not specified
• Target Recruitment: 42

Inclusion Criteria

Forty two infants admitted with bronchiolitis, who needed more than 40% oxygen therapy to maintain normal levels of arterial oxygen saturation. This was a pilot study. Forty two patients were enrolled between January 1991 and April 1992 in two paediatric hospitals in England (North Staffordshire Hospital and Royal Berkshire Hospital) if they fulfilled the following criteria:
1. Clinical diagnosis of bronchiolitis (irrespective of whether respiratory syncitial virus was isolated)
2. Age 1 year
3. Presence of respiratory failure with fractional inspired oxygen (FiO2) 0.4 to achieve an arterial oxygen saturation (SaO2) of 96-99%.

Exclusion Criteria

Infants with bronchopulmonary dysplasia (BPD), congenital cardiac, pulmonary or neuromuscular diseases or signs of upper airway obstruction were excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ot provided at time of registration

Secondary Outcome Measures

Name	Time	Method
ot provided at time of registration