Adipose Tissue Imaging in Patients with Type 2 Diabetes, Pilot Study

Completed

• Conditions: type 2 diabetes; 10018424

• Registration Number: NL-OMON40449
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Age>= 18 years
BMI 27-40
For healthy volunteers: Fasting blood glucose< 6.1 mmol/l, HbA1c< 42 mmol/mol (6%)
For patients with T2D: Clinical overt T2D, on a glucose-lowering diet or on oral glucose-lowering medication, stable and under control for minimal 2 years, HbA1c< 75 mmol/mol (9%)

Exclusion Criteria

Renal dysfunction with MDRD< 60
Overt symptomatic neuropathy or proliferative retinopathy
A history of cardiovascular disease complications (myocardial infarction, stroke, peripheral artery disease)
Pregnancy or lactating
Receiving subcutaneous insulin
Incapability to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>FDG uptake in visceral, subcutaneous abdominal, and gluteofemoral adipose<br /><br>tissue.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>