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Clinical Trials/NCT00508066
NCT00508066
Completed
Phase 4

Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery

Shriners Hospitals for Children1 site in 1 country60 target enrollmentMay 2007

Overview

Phase
Phase 4
Intervention
Bupivacaine
Conditions
Scoliosis
Sponsor
Shriners Hospitals for Children
Enrollment
60
Locations
1
Primary Endpoint
VAS pain score
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the effects of continuous local anesthetic delivery on the immediate post-op recovery of patients undergoing spinal fusion surgery for congenital or idiopathic scoliosis.

Detailed Description

Constant local analgesic infusion is a relatively new modality that provides a constant supply of medication without the need for repeat injections. This method has shown encouraging results with respect to pain levels, narcotic use, faster rehabilitation and shorter hospital stay in patients undergoing laparotomies, iliac crest bone graft harvest, and sternotomies. In addition, there have not been any reported complications when used in these scenarios. We hope to confirm better pain control, less narcotic use (i.e. PCA), fewer narcotic side effects, better response to physical therapy and earlier discharge. Which may be generalized to the spinal surgery patient population as less pain and suffering and a better overall hospital course

Registry
clinicaltrials.gov
Start Date
May 2007
End Date
January 2011
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Terri Green

Clinical Data Coordinator

Shriners Hospitals for Children

Eligibility Criteria

Inclusion Criteria

  • Clinical Diagnosis of Congenital Scoliosis
  • Clinical Diagnosis of Idiopathic Scoliosis
  • Anticipated Spinal Fusion Surgery

Exclusion Criteria

  • Less than 8 years of age

Arms & Interventions

Arm 1

Subjects in arm 1 will intraoperatively have a continuous infusion catheter placed in the paraspinal musculature of the posterior spinal wound. Post-operatively, the catheter will infuse 0.25 - 0.5% (according to patient's weight) Bupivacaine at a rate of 4ml/hr for 72 hours. This is in addition to the standardized PCA pain management.

Intervention: Bupivacaine

Arm 2

Subjects in arm 2 will intraoperatively have a continuous infusion catheter placed in the paraspinal musculature of the posterior spinal wound. Post-operatively, the catheter will infuse normal saline at a rate of 4ml/hr for 72 hours. This is in addition to the standardized PCA pain management.

Intervention: Normal Saline

Outcomes

Primary Outcomes

VAS pain score

Time Frame: 72 hours

Secondary Outcomes

  • Physical Therapy Progress(Post-op day 1, 2, 3)

Study Sites (1)

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