Platelet function in minimal extracorporeal circulation versus conventional extracorporeal circulation in coronary artery bypass grafting

• Conditions: platelet dysfunction; thrombocytopathy; 10035534; 10011082; 10003184

• Registration Number: NL-OMON37082
• Lead Sponsor: anaesthesiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

- patients undergoing non emergency coronary artery bypass grafting using conventional extracorporeal circulation or minimal extracorporeal circulation
- 18 years and older
- left ventricle function >50%

Exclusion Criteria

- emergency setting
- platelet function disorders before surgery
- thrombocytopenia
- renal insufficiency
- use of clopidogrel shorter than 5 days before surgery
- chronic alcohol abuse

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Results tromboelastography and multiple electrode aggregometry </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>perioperative blood loss<br /><br>blood loss every hour after PACU/IC admission for 4 hours<br /><br>total blood loss 24 hours after CABG<br /><br>total amount of transfused packed cells perioperative<br /><br>total amount of transfused packed cells 24 hours after CABG<br /><br>total amount of transfused platelets perioperative<br /><br>total amount of transfused platelets 24 hours after CABG<br /><br>total amount of transfused fresh frozen plasma perioperative<br /><br>total amount of transfused fresh frozen plasma 24 hours after CABG</p><br>