Electrogastrography as potential diagnostic test in patients with gastric ischemia

Completed

Conditions: Chronic Splanchnic Syndrome (CSS)
enduring blood shortage to abdominal organs
10018031
10003216

Registration Number: NL-OMON39396

Lead Sponsor: Medisch Spectrum Twente

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 24

Inclusion Criteria

Healthy subjects: above 18 years of age. Normal abdominal arteries (no chronic splanchnic syndrome, CSS) verified using abdominal duplex ultrasound. Able to sit or lay down for 150 minutes.;Subjects with splanchnic ischemia: above 18 years of age. Proven chronic splanchnic syndrome, with abnormal tonometry. Able to sit or lay down for 150 minutes.

Exclusion Criteria

Healthy subjects should not suffer from symptoms or disease based on the gastrointestinal tract. No disease concerning cardiatric, pulmonary or internal medicine area's. Pregnant women. Wheelchair bound.
Subjects with splanchnic ischemia: pregnant women. wheelchair bound. Presence of gastroparesis

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To determine whether patients with gastric ischemia have different EGG signals<br /><br>after a meal in comparison to healthy controls. Specifically we will be<br /><br>examining changes in basic rhythm (ECA) and propulsion speed between the<br /><br>different groups in a fasting state and after a test meal. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1) Determine whether a difference in HR-EGG is detectable between single and<br /><br>multiple CSS patients. We expect the latter to have much larger abnormalities<br /><br>than the first<br /><br>2) Determine whether HR-EGG differences are seen in the healthy volunteer group<br /><br>when measured on different days (reproducibility)<br /><br>3) Determine to what extent the under 2 noted differences could influence the<br /><br>primary study outcome<br /><br>4) Determine to what extent the basic rhythm and/or propulsion speed in the<br /><br>HR-EGG normalizes in post intervention patients.<br /><br>5) Determine to what extent EGG differs in people suffering from abdominal<br /><br>ischemia and patients suffering from both abdominal ischemia and diabetes<br /><br>mellitus. </p><br>