NCT05683873招募中不适用
Stroke-induced Myocardial Dysfunction: Role of GDF-15 (SMOG-15) Clinical Work Package
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 130
- 试验地点
- 2
- 主要终点
- Global Longitudinal Strain (GLS) of the left ventricle measured by trans-thoracic ultrasound (TTE)
研究概览
简要总结
The aim of this study is to analyze the relationship between the blood biomarker GDF-15 and heart damage after stroke.
It is being conducted in France, in the Neurology Department of the Dijon University Hospital (Burgundy). The research is interventional because a biological blood test will be performed, as well as a heart rhythm recording and several cardiac echograms during the hospitalization of the participants and during the follow-up consultation scheduled 4 to 6 months after the stroke.
A total of 130 stroke patients will participate in this study.
Participation includes 4 visits:
- Inclusion visit (within 24 hours of the first stroke symptoms)
- visit 1 (within 24 to 72 hours of stroke)
- visit 2 (within 48 hours of visit 1)
- Visit 3 (approximately 4-6 months post-stroke)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult with acute symptomatic cerebral infarction documented by brain imaging on admission (cerebral angioscan or cerebral MRI)
- •Whose first symptoms appeared within 24 hours before inclusion
- •Whose consent to participate in this study was obtained from the patient or a close relative.
排除标准
- •Person with a history of symptomatic stroke, either ischemic or hemorrhagic
- •Anyone with a history of heart disease including: atrial fibrillation or flutter (known or discovered on admission), chronic heart failure, pacemaker, defibrillator, or other cardiac devices
- •Person with acute heart failure, suspected infective endocarditis, STEMI, or concurrent pulmonary embolism
- •A person who is not a member or beneficiary of a social security system
- •Person deprived of liberty
- •Person subject to a legal protection measure (curatorship, guardianship)
- •Person subject to a legal protection measure
- •Pregnant, parturient or breastfeeding woman
结局指标
主要结局
Global Longitudinal Strain (GLS) of the left ventricle measured by trans-thoracic ultrasound (TTE)
时间窗: within 24 to 72 hours post-stroke
次要结局
未报告次要终点
研究者
研究点 (2)
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