Occupational Therapy-Based Cognitive Rehabilitation of Cocaine Abusers: A Pilot Study

University of California, San Francisco1 site in 1 country50 target enrollmentJuly 2013

ConditionsMild Cognitive Impairment, So Stated Cocaine Use Disorder

Overview

Phase: N/A
Intervention: Not specified
Conditions: Mild Cognitive Impairment, So Stated
Sponsor: University of California, San Francisco
Enrollment: 50
Locations: 1
Primary Endpoint: Change in cognitive impairment
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study integrates a model of occupational-therapy based cognitive rehabilitation as part of a comprehensive treatment plan for cocaine abusers. We hypothesize that cognitive impairment and quality of life would improve and that cocaine use would decrease in those participants receiving occupational-therapy based cognitive rehabilitation.

Detailed Description

occupational-therapy based cognitive rehabilitation as part of a comprehensive treatment plan for cocaine abusers

Registry

clinicaltrials.gov

Start Date

July 2013

End Date

March 31, 2019

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of California, San Francisco

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Primary cocaine use disorder (based on DSM-5 criteria) and in at least 3 months of remission
•At least mild cognitive impairment, defined as = or \> 1.5 standard deviations impairment on any 2 performance-based neurocognitive measures
•Needing to change quality of life, defined as self-identifying at least 2 life areas as needing to change on the Drug User Quality of Life Scale
•A Veteran at the San Francisco Veterans Affairs Medical Center
•Currently receiving weekly drug counseling (individual or group; at least 1 hour/week) through an outpatient substance use disorder treatment program

Exclusion Criteria

•Inability to speak, read, write, and understand English
•Inadequate hearing or vision
•Concurrent substance use disorder (except tobacco or caffeine) not in at least 3 months of remission
•A psychiatric disorder that will interfere with study participation or will make participation hazardous (e.g., psychosis, suicidal or homicidal ideations, severe anxiety)
•A depressive disorder classified as severe, defined as a Beck Depression Inventory-II score \>29
•Current diagnosis of a bipolar disorder needing acute inpatient psychiatric hospitalization
•Currently symptomatic from attention-deficit/hyperactivity disorder (DSM-5 criteria)
•Any learning disorder, any type of dementia, any type of delirium, or an amnestic disorder due to any general medical condition
•Wechsler Test of Adult Reading standard score \<70
•Mini-Mental State Examination score \<24