Italian Validation of the Beaumont Behavioural Inventory (BBI)
Completed
- Conditions
- Amyotrophic Lateral Sclerosis
- Interventions
- Behavioral: BBI
- Registration Number
- NCT04440644
- Lead Sponsor
- Istituti Clinici Scientifici Maugeri SpA
- Brief Summary
Up to 50% of patients affected with amyotrophic lateral sclerosis (ALS) can show behavioral dysfunctions within the spectrum of frontotemporal degenerations (FTD) - namely, apathy, disinhibition, loss of sympathy/empathy, perseverative and stereotyped behaviours, dietary changes \[Strong et al., 2017\].
The Beaumont Behavioural Inventory (BBI) \[Elamin et al., 2017\] is a questionnaire designed for detecting FTD-spectrum behavioural changes in ALS patients. The present study aims at both validating the BBI in an Italian ALS population and determining normative cut-off values of the instrument.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 190
Inclusion Criteria
- possible, probable or definite ALS according to El Escorial revised criteria
Exclusion Criteria
- Any other clinically significant cardiovascular, gastrointestinal, hepatic, renal, neurological or psychiatric disorder or any other major concurrent illness that in the opinion of the investigator could interfere with the interpretation of the study results
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Healthy control BBI healthy control participants Patients BBI patients with amyotrophic lateral sclerosis
- Primary Outcome Measures
Name Time Method Beaumont Behavioural Inventory 2 years Psychometrics
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
ICS Maugeri
🇮🇹Milano, Italy