Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in Lesion Sterilization and Tissue Repair (LSTR) for the Treatment of Necrotic Primary Molars: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 主要终点
- Tenderness to percussion
研究概览
简要总结
The aim of this study is to evaluate and compare the clinical effectiveness of zinc oxide-propolis mixture with triple antibiotic paste in LSTR as root canal filling material in necrotic primary molars.
详细描述
The promising results of propolis as a natural antibiotic in previous in- vivo studies made it interesting to combine propolis to the golden standard zinc oxide eugenol as an intracanal medication in pulp affected primary molars and use this mix as a natural substitute to the modified triple antibiotic paste (m-TAP) and therefore overcoming the antibiotic bacterial resistance, allergy and developmental anomalies that might arise in permanent successor teeth from m-TAP usage.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Double
入排标准
- 年龄范围
- 4 Years 至 7 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children:
- •Cooperative children aged 4 -7 years old.
- •Systemically healthy.
- •Clinical criteria:
- •Necrotic primary mandibular second molar teeth.
- •Spontaneous pain or tenderness to percussion
- •Deep carious lesion with pulp exposure.
- •Presence of chronic apical abscess or sinus tract Tooth should be restorable. (Thakur et al., 2021)
- •Radiographic criteria:
- •Coronal-radiographic evidence of a deep carious lesions or lesion approximating pulp
- •Radicular discontinuity of lamina dura, furcation involvement less than or equal to half of shortest root in vertical dimension. (Thakur et al., 2021)
排除标准
- •Children:
- •With physical or emotional alteration.
- •Children with systemic disease.
- •Previous history of allergy to antibiotics used in the study.
- •Children that will not attend follow up. • Teeth:
- •Non restorable carious primary molars.
- •Grade III mobility
结局指标
主要结局
Tenderness to percussion
时间窗: 1 year
(binary outcome measured by percussion test using back of the dental mirror
Postoperative pain
时间窗: 1 year
Binary outcome measured with direct questioning to the patient
Swelling / sinus tract
时间窗: 1 year
binary outcome measured with visual examination of the patient examination of the patient
Mobility
时间窗: 1 year
(measured by mobility test) and according to Miller's Grades; reduction in grade of mobility from preoperative baseline was treated as success
次要结局
- Radiographic success(6 months)
研究者
Sara Khaled Adam
Assistant lecturer pediatric dentistry
Cairo University